Messi made a spectacular return from two months out in the first-leg at the Camp Nou last week as he scored twice as a second-half substitute to give Barca a commanding 4-0 lead.

And he also played the entire second period in Barca's 0-0 draw against joint La Liga leaders Atletico Madrid on Saturday.

Brazilian forward Neymar also returns to the starting line-up for the first time in four matches as Martino makes nine changes in all from the side that started against Atletico.