Nadal starts season with loss to Ferrer in Abu Dhabi
Spain's Rafael Nadal returns the ball to his compatriot David Ferrer during their semi-final on the second day of the Mubadala World Tennis Championship in the Emirati capital Abu Dhabi on December 27, 2013
It was the world number one's first match since losing in straight sets to Novak Djokovic in the final of the World Tour Finals in London on November 11.
Playing ahead of the official ATP season-opener in nearby Doha next week, Ferrer looked the sharper from the start, breaking in the ninth game to take the first set.
It was more of the same in the second set as Nadal struggled to find his range against an opponent who already had a game under his belt, having defeated Stanislas Wawrinka in the quarter-finals on Thursday.
"I think the fact that I had already played a game on the same surface meant that I was better prepared than Rafa," said Ferrer.
"I am happy with the state of my game and will look to produce my best tennis for the final."
The second semi-final, played later on Friday, sees world number two Djokovic go up against Jo-Wilfried Tsonga of France.
In earlier action, Andy Murray chalked up his first win since returning to action after a three-month injury lay-off by defeating Switzerland's Wawrinka 6-3, 6-4.
The 26-year-old Wimbledon champion had back surgery in September and did not play again until he lost to Tsonga in the quarter-finals of the exhibition tournament on Thursday.
Wawrinka lost to Ferrer on the same day and the match between him and Murray was to decide who would finish fifth in the unofficial three-day tournament that saw Nadal and Djokovic joining in at the semi-final stage.
Murray looked much sharper against Ferrer than he had looked in the second set against Tsonga and had little difficulty in seeing off the challenge of the world number eight.
The world number four got the better of three successive breaks to take the first set and then forged ahead again with a break for 4-3 in the second.
Wawrinka saved a match point on his own serve with a forehand winner, but Murray confidently served out for the victory.
In a courtside interview Murray said: "I feel pretty good, a lot better than I did a few months ago. I just need to play more matches like this because the intensity's a lot higher than you can get in practice.
"It was good to get two matches against top players. Everyone needs matches at this stage, especially me. It's been a perfect start and hopefully I'll get better."
Murray will next make the short trip over to Doha where he will play in the AFP season-opener tournament.