Scotland make four changes for Boks clash
Scotland's scrum-half Henry Pyrgos eyes the ball during the Six Nations Rugby Union match between France and Scotland at the Stade de France, in Saint-Denis, near Paris on March 16, 2013 - by Franck Fife
Henry Pyrgos will start at scrum-half in Port Elizabeth in place of Grayson Hart, while Tim Swinson and Chris Fusaro start in the pack and 20-year-old Glasgow Warriors number eight Adam Ashe makes his Test debut.
"He is a talented player and the reports of his form in New Zealand have been very positive," said recently installed Cotter, who is hoping to continue his 100 percent wining record with Scotland.
"He's trained well with us and looked sharp. He is a specialist Number Eight and this is a golden opportunity for him.”
Under Cotter's tenure the Scots have beaten the United States, Canada and Argentina.
But his men face a tough test against a South Africa side coming off the back of a two-nil Test sweep against Wales.
"I've always regarded playing South Africa in South Africa as the benchmark. It's a massive challenge and it gives our boys an opportunity to lift their level," said Cotter.
"If we can make accurate choices in the way we play and impose our form of rugby then I think that will be a shift in the right direction."
Scotland team to play South Africa in Port Elizabeth on Saturday:
Stuart Hogg, Sean Maitland, Nick De Luca, Peter Horne, Tommy Seymour, Duncan Weir, Henry Pyrgos, Adam Ashe, Chris Fusaro, Robert Harley, Grant Gilchrist (capt), Tim Swinson, Geoff Cross, Ross Ford, Alasdair Dickinson.
Replacements: Kevin Bryce, Moray Low, Euan Murray, Jonny Gray, Tyrone Holmes, Grayson Hart, Dougie Fife, Peter Murchie.