Serena has Evert, Navratilova in her sights
Serena Williams plays a shot during a practice session, ahead of the Australian Open tournament, in Melbourne, on January 11, 2014
The 32-year-old enters the opening Grand Slam of the season next week in formidable form, losing just five matches last year and winning the Brisbane International earlier this month.
She is gunning for a sixth Australian Open crown, which would move her alongside Evert and Navratilova and further underline her reputation as one of the greatest women players ever seen.
Ahead of Melbourne, Navratilova said she expects Williams to match the record this month and go on to surpass Steffi Graf's 22 titles to become the most successful Grand Slam champion in the Open era.
Williams said it would be an honour to be in the same company as Evert and Navratilova, but she was taking nothing for granted after an injury-hit campaign last year ended with defeat to young fellow American Sloane Stephens in the quarter-finals.
"It would mean a lot to be on the same level as such great players as Chris Evert and Martina Navratilova," she said.
"I still have a lot of work to do. I obviously want to be able to reach that level, but I'm not there yet. Hopefully I'll get there."
The top seed, who opens her campaign against Australia's Ashleigh Barty, is in such hot form that her French coach Patrick Mouratoglou on Thursday said she could pull off the "exceptional" achievement of sweeping all four Grand Slams in 2014.
"It's happened just a few times in the history of tennis -- but she can do it and the goal is to do the best possible in all four Grand Slams," he said.
Williams completed a non-calendar Grand Slam in 2003 and last year won the French Open and the US Open.
To keep the dream alive Williams will have to deal with some extreme weather with temperatures set to soar above 40 Celsius (104 Fahrenheit) early next week.
She said she was not looking forward to the heat, but added that she could cope.
"I've been training my whole life in the heat. I think I'm pretty used to it," said the Florida-based American.
"I mean, obviously the heat in Melbourne is just completely different than any other heat.
"But it's okay. I just got to be ready to play under any circumstances."
Williams' preperations have been perfect, she said, with victory over world number two and defending Australian Open champion Victoria Azarenka in Brisbane, then court time and acclimatisation in Melbourne over the past week.
"Right now I feel pretty good. Felt pretty good the last at least year," she said.
"I think it was great preparation. Brisbane I think is a great tournament to play to get prepared for Melbourne. And also I think it's a good time to have a week to train in Melbourne before the tournament actually begins."
She should have little trouble dispatching Barty first up, but said she never took anything for granted.
"She's extremely talented. She moves well. She plays well. She serves well. She has good returns. I saw her play a little bit at Brisbane. I was actually super impressed with her game," she said of the 153-ranked player in the world.
"I think it will be a great opportunity for us both. I take every match as it comes and see how it goes. I try not to put too much pressure on myself."
Williams is seeded to face Italy's seventh seed Sara Errani in the quarters before a potential semi-final clash with fourth-seeded Li Na.